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When a close family member was diagnosed with age-related macular degeneration (AMD), Karen and the late Herbert Lotman began asking questions. What they found was little was known about the causes and effects of this devastating disease that leaves millions of people around the world with little sight and little hope of ever restoring it.

So they set out to change that, founding the Macula Vision Research Foundation (MVRF) as a 501(c)(3) public charity in 1997.

The Lotmans’ exuberant passion and dedication to curing macular degeneration leads MVRF in a fearless fight for the cure. Studies conducted by leading vision scientists and funded by MVRF have led to some of the greatest breakthroughs of the last decade.

In 2018, The Karen and Herbert Lotman Fund of the Macula Vision Research Foundation of the University of Pennsylvania Scheie Eye Institute was created.